Attaullah Khogyani, a spokesperson for the provincial government, said the explosion took place at around 8:30 am local time close to Customs House of Nangarhar.
Khogyani further added that a roadside bomb went off close to a civilian vehicle, killing one person and wounding at least three others.
He also added that the wounded individuals have been shifted to hospital where they are receiving treatment and their health condition has been reported as satisfactory.
No individual or group including Taliban has so far claimed responsibility for the incident.