The Taliban were targeted last night and this morning in suburb of Lashkargah and Nahersaraj districts.
The Taliban were suppressed after attack on them on several security posts.
Security official of Helmand in south of country told media, 13 Taliban were killed and number of others were injured in air and ground raids.
This is the first attack by US troops since the final US peace deal with Taliban in Afghanistan.
Another report says, police of Helmand discovered and confiscated 14 mines from crowded roads of the province and prevented from a series of blasts.
Security officials of the province blamed Taliban for the failed mine planting.