Two Nato soldiers were killed in an insurgents' attack in eastern Afghanistan on Sunday, Isaf said.
It provided no other details on the attacks, including the nationalities of the troops.
It comes as four Nato troops were killed in separate roadside bomb attacks in southern Afghanistan on Saturday.
The death brings the number of foreign troops to 167 so far this year in the Afghan war, according to the Icasulaties.org website that tracks the foreign troop's casualties in Afghanistan.
There are about 130, 000 foreign troops in Afghanistan, 90,000 of which are US forces.