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PublishDate: Wednesday, October 20, 2021 09:58

US surgeons successfully test pig kidney transplant in human patient

For the first time, a pig kidney has been transplanted into a human without triggering immediate rejection by the recipient’s immune system, a potentially major advance that could eventually help alleviate a dire shortage of human organs for transplant.

Afghan Voice Agency (AVA)_The procedure done at Langone Health in City involved use of a pig whose genes had been altered so that its tissues no longer contained a molecule known to trigger almost immediate rejection.

The recipient was a brain-dead patient with signs of kidney dysfunction whose family consented to the experiment before she was due to be taken off of life support, researchers told Reuters.

For three days, the new was attached to her blood vessels and maintained outside her body, giving researchers access to it.

Test results of the transplanted kidney’s function “looked pretty normal,” said transplant surgeon Dr. Robert Montgomery, who led the study.

The kidney made “the amount of urine that you would expect” from a transplanted human kidney, he said, and there was no evidence of the , early rejection seen when unmodified are transplanted into -human_primates.

The recipient’s abnormal creatinine level – an indicator of poor kidney function – returned to normal after the transplant, said.

In the United States, nearly 107,000 people are presently waiting for organ transplants, including more than 90,000 awaiting a kidney, according to the United Network for . Wait times for a kidney average three-to-five years.

Researchers have been working for decades on the possibility of using animal organs for transplants, but have been stymied over how to prevent immediate rejection by the human body.

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